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KMID : 1144320120440060465
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감염과 화학요법
2012 Volume.44 No. 6 p.465 ~ p.468
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Multicystic Mass Infection in the Subcutaneous Tissue around Joint Developed by Aspergillus in a Liver Transplant Patient
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Song Je-Eun
Oh Dong-Hyun
Kim Min-Hyung
Kim Yong-Chan
Ahn Jin-Young
Jeong Su-Jin
Ku Nam-Su
Kim Hye-Won
Kim Sun-Bean
Han Sang-Hoon
Choi Jun-Yong
Kim Chang-Oh
Song Young-Goo
Kim June-Myung
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Abstract
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Invasive aspergillosis can be occured in immune-compromised patients with hematopoietic stem cell transplantation, solid organ transplantation and prolonged neutropenia. The major area of invasive aspergillosis involves the sinopulmonary tract but can occur around the joint areas rarely. A 72-year-old man, who had received a liver transplant 6 years earlier, presented with a mass lesion around the right knee joint that developed 3 year earlier. Knee MRI revealed a multicystic subcutaneous mass around the knee joint. An excision was performed, and many fungal hyphae that were morphologically most consistent with Aspergillus spp. were observed in tissue. After amphotericin B therapy for 2 weeks, the patient did not show any evidence of a recurrence of invasive aspergillosis for 15 months. As Aspergillus spp. can cause a range of infections in solid organ transplants, invasive aspergillosis must be considered in patients with a recurrent cystic mass lesion.
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KEYWORD
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Aspergillus, Liver transplantation, Cysts
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